BRIVIACT is a federally managed material (CV) mainly because it can be abused or produce dependence. Maintain BRIVIACT in a secure spot to forestall misuse and abuse. Marketing or freely giving BRIVIACT may well damage Other people and is also versus the regulation.

fluvoxamine will raise the level or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

Use Caution/Observe. Ethinyl estradiol may possibly inhibit the clearance of benzodiazepines that undergo oxidation, thus raising serum concentrations of concomitantly administered benzodiazepines.

I couldn’t just get up several hours immediately after my seizures like I accustomed to and become alright. Instead, it took two or three days to totally Get well from Every seizure. Which’s how factors progressed into my teenager many years.”

miconazole vaginal will enhance the level or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

Reserve concomitant prescribing of these prescription drugs for use in clients for whom option treatment method choices are inadequate

B: Might be acceptable. Either animal scientific studies show no chance but human studies not offered or animal scientific tests showed small threats and human experiments completed and showed no threat.

Active metabolites: N-desmethyldiazepam and temazepam, which can be each additional metabolized to oxazepam; mostly eradicated by get more info glucuronidation

A call to prescribe diazepam rectal gel includes greater than the prognosis and variety of suitable dose

Istradefylline 40 mg/day increased peak levels and AUC of CYP3A4 substrates in scientific trials. This impact was not observed with istradefylline 20 mg/day. Take into consideration dose reduction of delicate CYP3A4 substrates.

triclabendazole will raise the degree or effect of diazepam by influencing hepatic enzyme CYP2C19 metabolism.

Utilization of benzodiazepines, which includes diazepam, both of those made use of by yourself and in combination with other CNS depressants, may bring on perhaps lethal respiratory depression

lasmiditan, diazepam. Either boosts outcomes of the other by sedation. Use Warning/Keep an eye on. Coadministration of lasmiditan together with other CNS depressant medicine, including alcohol haven't been evaluated in scientific experiments. Lasmiditan may perhaps lead to sedation, together with other cognitive and/or neuropsychiatric adverse reactions.

If unable to stay away from coadministration of belzutifan with sensitive CYP3A4 substrates, look at escalating the delicate CYP3A4 substrate dose in accordance with its prescribing facts.